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Clathrin-mediated Endocytosis of MUC1 Is Modulated by Its Glycosylation State

MUC1 is a mucin-like type 1 transmembrane protein associated with the apical surface of epithelial cells. In human tumors of epithelial origin MUC1 is overexpressed in an underglycosylated form with truncated O-glycans and accumulates in intracellular compartments. To understand the basis for this a...

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Bibliografski detalji
Glavni autori: Altschuler, Yoram, Kinlough, Carol L., Poland, Paul A., Bruns, James B., Apodaca, Gerard, Weisz, Ora A., Hughey, Rebecca P.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC14813/
https://ncbi.nlm.nih.gov/pubmed/10712502
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