Biochemical and genetic characterization of the DNA ligase encoded by Saccharomyces cerevisiae open reading frame YOR005c, a homolog of mammalian DNA ligase IV.

Here we demonstrate that the Saccharomyces cerevisiae DNA ligase activity, which we previously designated DNA ligase II, is encoded by the genomic DNA sequence YOR005c. Based on its homology with mammalian LIG4, this yeast gene has been named DNL4 and the enzyme activity renamed Dnl4. In agreement w...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Ramos, W, Liu, G, Giroux, C N, Tomkinson, A E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9837999/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.24.5676
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