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Upgrading antibiotic use within a class: Tradeoff between resistance and treatment success

Increasing resistance to antibiotics creates the need for prudent antibiotic use. When resistance to various antibiotics within a class is driven by stepwise accumulation of mutations, a dilemma may exist in regard to replacing an antibiotic that is losing effectiveness due to resistance with a new...

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Detalhes bibliográficos
Main Authors: Wang, Y. Claire, Lipsitch, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480462/
https://ncbi.nlm.nih.gov/pubmed/16772381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600636103
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