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Fitness cost of LINE-1 (L1) activity in humans

The self-replicating LINE-1 (L1) retrotransposon family is the dominant retrotransposon family in mammals and has generated 30–40% of their genomes. Active L1 families are present in modern mammals but the important question of whether these currently active families affect the genetic fitness of th...

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Autors principals: Boissinot, Stephane, Davis, Jerel, Entezam, Ali, Petrov, Dimitri, Furano, Anthony V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480451/
https://ncbi.nlm.nih.gov/pubmed/16766655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603334103
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