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Identification of point mutations in mixtures by capillary electrophoresis hybridization.

We have developed a rapid method for unambiguous identification and mutant fraction determination of individual mutants in mixtures of DNA sequence variants each differing by one or a few nucleotides. This method has applications to such diverse areas as interpretation of mutational spectra, screeni...

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Bibliografische gegevens
Hoofdauteurs: Khrapko, K, Coller, H A, Hanekamp, J S, Thilly, W G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148045/
https://ncbi.nlm.nih.gov/pubmed/9838007
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