Identification of point mutations in mixtures by capillary electrophoresis hybridization.

We have developed a rapid method for unambiguous identification and mutant fraction determination of individual mutants in mixtures of DNA sequence variants each differing by one or a few nucleotides. This method has applications to such diverse areas as interpretation of mutational spectra, screeni...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Khrapko, K, Coller, H A, Hanekamp, J S, Thilly, W G
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1998
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148045/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9838007/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.24.5738
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