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A mechanism of translational repression by competition of Paip2 with eIF4G for poly(A) binding protein (PABP) binding
The eukaryotic mRNA 3′ poly(A) tail and the 5′ cap cooperate to synergistically enhance translation. This interaction is mediated by the cap-binding protein eIF4E, the poly(A) binding protein (PABP), and eIF4G, a scaffolding protein that bridges between eIF4E and PABP to bring about the circularizat...
Tallennettuna:
| Päätekijät: | , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2006
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1480435/ https://ncbi.nlm.nih.gov/pubmed/16772376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603701103 |
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