LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY

Pretreatment of animals with butyrylcholinesterase (EC 3.1.1.8 BChE) provides complete protection from the acute effects of organophosphorus nerve agents. Butyrylcholinesterase has also been shown to protect from cocaine toxicity. Large amounts of highly purified butyrylcholinesterase are needed to...

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Bibliographic Details
Main Authors:	Lockridge, Oksana, Schopfer, Lawrence M., Winger, Gail, Woods, James H.
Format:	Artigo
Language:	Inglês
Published:	2005
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1480358/ https://ncbi.nlm.nih.gov/pubmed/16788731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1901/jaba.2005.3-nihms5095
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LARGE SCALE PURIFICATION OF BUTYRYLCHOLINESTERASE FROM HUMAN PLASMA SUITABLE FOR INJECTION INTO MONKEYS; A POTENTIAL NEW THERAPEUTIC FOR PROTECTION AGAINST COCAINE AND NERVE AGENT TOXICITY

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