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The mechanism of actinomycin D-mediated inhibition of HIV-1 reverse transcription.

The mechanism of reverse transcription was analyzed in vitro with RNA templates and the reverse transcriptase (RT) enzyme of human immunodeficiency virus type 1 (HIV-1). In particular, we analyzed the mechanism of actinomycin D (ActD) mediated inhibition of the strand transfer step, in which the new...

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Autores principales: Jeeninga, R E, Huthoff, H T, Gultyaev, A P, Berkhout, B
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC148019/
https://ncbi.nlm.nih.gov/pubmed/9826774
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