Induced TRPC1 expression sensitizes intestinal epithelial cells to apoptosis by inhibiting NF-κB activation through Ca(2+) influx

Apoptosis occurs within crypts and at the intestinal luminal surface and plays a critical role in mucosal homoeostasis. NF-κB (nuclear factor-κB) is the central regulator of the transcription of genes involved in apoptosis, and its activity is highly regulated in the intestinal mucosa. We have recen...

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Detalhes bibliográficos
Main Authors: Marasa, Bernard S., Rao, Jaladanki N., Zou, Tongtong, Liu, Lan, Keledjian, Kaspar M., Zhang, Ai-hong, Xiao, Lan, Chen, Jie, Turner, Douglas J., Wang, Jian-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479765/
https://ncbi.nlm.nih.gov/pubmed/16551274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060124
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