Increased p53 activity does not accelerate telomere-driven ageing

There is a great interest in determining the impact of p53 on ageing and, for this, it is important to discriminate among the known causes of ageing. Telomere loss is a well-established source of age-associated damage, which by itself can recapitulate ageing in mouse models. Here, we have used a gen...

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Bibliografiske detaljer
Main Authors: García-Cao, Isabel, García-Cao, Marta, Tomás-Loba, Antonia, Martin-Caballero, Juan, Flores, Juana M, Klatt, Peter, Blasco, María A, Serrano, Manuel
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Scientific Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479549/
https://ncbi.nlm.nih.gov/pubmed/16582880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400667
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