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Increased p53 activity does not accelerate telomere-driven ageing
There is a great interest in determining the impact of p53 on ageing and, for this, it is important to discriminate among the known causes of ageing. Telomere loss is a well-established source of age-associated damage, which by itself can recapitulate ageing in mouse models. Here, we have used a gen...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479549/ https://ncbi.nlm.nih.gov/pubmed/16582880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400667 |
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