ロード中...

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

CTL-associated antigen 4 (CTLA4) blockade releases inhibitory controls on T cell activation and proliferation, inducing antitumor immunity in both preclinical and early clinical trials. We examined the mechanisms of action of anti-CTLA4 and a GM-CSF–transduced tumor cell vaccine (Gvax) and their imp...

詳細記述

保存先:
書誌詳細
主要な著者: Quezada, Sergio A., Peggs, Karl S., Curran, Michael A., Allison, James P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479425/
https://ncbi.nlm.nih.gov/pubmed/16778987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27745
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!