Cationic oligonucleotides can mediate specific inhibition of gene expression in Xenopus oocytes.

Base-specific hydrogen bonding between an oligonucleotide and the purines in the major groove of a DNA duplex provide an approach to selective inhibition of gene expression. Oligonucleotide-mediated triplex formation in vivo may be enhanced by a number of different chemical modifications. We have pr...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Bailey, C P, Dagle, J M, Weeks, D L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147938/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9776745/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.21.4860
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