Isolation of a Human Monoclonal Antibody with Strong Neutralizing Activity against Diphtheria Toxin

We isolated a human monoclonal antibody against diphtheria toxin (DT). It bound to fragment B with a binding activity (K(d)) of 3.01 nM. The neutralizing activity assayed by the rabbit skin test was estimated to be 73,600 IU/g. This could be used as a therapeutic drug against DT in place of the trad...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kakita, Mai, Takahashi, Tsuyoshi, Komiya, Takako, Iba, Yoshitaka, Tsuji, Takao, Kurosawa, Yoshikazu, Takahashi, Motohide
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2006
Konular:
Microbial Immunity and Vaccines
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479265/
https://ncbi.nlm.nih.gov/pubmed/16714603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01731-05
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller