Members of a Legionella pneumophila Family of Proteins with ExoU (Phospholipase A) Active Sites Are Translocated to Target Cells

Legionella pneumophila replicates within alveolar macrophages, causing a severe pneumonia termed Legionnaires' disease. The bacterium resides within a vacuole that escapes immediate transport to the host lysosome. Instead, the vacuole interacts with the early secretory pathway to establish an e...

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Bibliographic Details
Main Authors: VanRheenen, Susan M., Luo, Zhao-Qing, O'Connor, Tamara, Isberg, Ralph R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479236/
https://ncbi.nlm.nih.gov/pubmed/16714592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02060-05
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