A formula for thermal stability (Tm) prediction of PNA/DNA duplexes.

An empirical formula for thermal stability (T m) prediction of PNA/DNA duplexes has been derived. The model is based on the T m as calculated for the corresponding DNA/DNA duplex employing a nearest neighbour approach, by including terms for the pyrimidine content and length of the PNA to take into...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Giesen, U, Kleider, W, Berding, C, Geiger, A, Orum, H, Nielsen, P E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1998
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9776766/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.21.5004
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