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Caspofungin Susceptibility in Aspergillus and Non-Aspergillus Molds: Inhibition of Glucan Synthase and Reduction of β-d-1,3 Glucan Levels in Culture
Caspofungin inhibits synthesis of β-d-1,3 glucan, essential to cell walls in Candida and Aspergillus spp., but activity against less common molds is largely uncharacterized. We demonstrate that caspofungin inhibits β-d-1,3 glucan synthesis and reduces in vitro growth of clinical isolates from the ge...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479154/ https://ncbi.nlm.nih.gov/pubmed/16723587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01610-05 |
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