Efficacy of Caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans

The echinocandin caspofungin is a potent inhibitor of the activity of 1,3-β-d-glucan synthase from Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans. In murine models of disseminated infection, caspofungin prolonged survival and reduced the kidney fungal burden. Caspofungin was at le...

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Autors principals: Bowman, J. C., Abruzzo, G. K., Flattery, A. M., Gill, C. J., Hickey, E. J., Hsu, M. J., Nielsen Kahn, J., Liberator, P. A., Misura, A. S., Pelak, B. A., Wang, T. C., Douglas, C. M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693977/
https://ncbi.nlm.nih.gov/pubmed/17015628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00485-06
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