Targeting of nucleic acid junctions: addressing to a branch point an oligodeoxynucleotide conjugated with an intercalator.

It is possible to enhance targeting of a DNA stem flank domain with a complementary DNA when it is conjugated with diphenyl ether at the branch point. The nucleoside 2'-deoxy-5-methyl- N 4-(4-phenoxyphenyl)cytidine (5) was synthesized from thymidineby tritylation, acetylation, amination via 2,4, 6-t...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Ali, O M, Franch, T, Gerdes, K, Pedersen, E B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147914/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9776754/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.21.4919
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