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Targeting of nucleic acid junctions: addressing to a branch point an oligodeoxynucleotide conjugated with an intercalator.

It is possible to enhance targeting of a DNA stem flank domain with a complementary DNA when it is conjugated with diphenyl ether at the branch point. The nucleoside 2'-deoxy-5-methyl- N 4-(4-phenoxyphenyl)cytidine (5) was synthesized from thymidineby tritylation, acetylation, amination via 2,4, 6-t...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Ali, O M, Franch, T, Gerdes, K, Pedersen, E B
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9776754/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.21.4919
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