Biosynthetic Pathway for Mannopeptimycins, Lipoglycopeptide Antibiotics Active against Drug-Resistant Gram-Positive Pathogens

The mannopeptimycins are a novel class of lipoglycopeptide antibiotics active against multidrug-resistant pathogens with potential as clinically useful antibacterials. This report is the first to describe the biosynthesis of this novel class of mannosylated lipoglycopeptides. Included here are the c...

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Bibliographic Details
Main Authors: Magarvey, Nathan A., Haltli, Brad, He, Min, Greenstein, Michael, Hucul, John A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2006
Subjects:
Chemistry; Biosynthesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479125/
https://ncbi.nlm.nih.gov/pubmed/16723579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01545-05
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