Helix 2 of the paired domain plays a key role in the regulation of DNA-binding by the Pax-3 homeodomain.

Eitemau Tebyg

• An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.
  gan: Vogan, K J, et al.
  Cyhoeddwyd: (1996)
• Analysis of the mouse Splotch-delayed mutation indicates that the Pax-3 paired domain can influence homeodomain DNA-binding activity.
  gan: Underhill, D A, et al.
  Cyhoeddwyd: (1995)
• The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain
  gan: Lam, Paula Y. P., et al.
  Cyhoeddwyd: (1999)
• The Oncogenic Potential of the Pax3-FKHR Fusion Protein Requires the Pax3 Homeodomain Recognition Helix but Not the Pax3 Paired-Box DNA Binding Domain
  gan: Lam, Paula Y.P., et al.
  Cyhoeddwyd: (1999)
• Lune/eye gone, a Pax-like protein, uses a partial paired domain and a homeodomain for DNA recognition
  gan: Jun, Susie, et al.
  Cyhoeddwyd: (1998)