The use of diaminopurine to investigate structural properties of nucleic acids and molecular recognition between ligands and DNA.
2,6-Diaminopurine (DAP) is an analogue of adenine which can be converted to nucleotides that serve as substrates for incorporation into nucleic acids by polymerases in place of (d)AMP. It pairs with thymidine (or uracil), engaging in three hydrogen bonds of the Watson-Crick type. The result of DAP i...
Guardat en:
| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1998
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147870/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742229/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4309 |
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