The stability of duplexes involving AT and/or G4EtC base pairs is not dependent on their AT/G4EtC ratio content. Implication for DNA sequencing by hybridization.
Sequencing by the recently reported hybridization technique requires the formation of DNA duplexes with similar stabilities. In this paper we describe a new strategy to obtain DNA duplexes with a thermal stability independent of their AT/GC ratio content. Melting data were acquired on 35 natural and...
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| 發表在: | Nucleic Acids Res |
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| Principais autores: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147843/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9722646/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.18.4249 |
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