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The stability of duplexes involving AT and/or G4EtC base pairs is not dependent on their AT/G4EtC ratio content. Implication for DNA sequencing by hybridization.

Sequencing by the recently reported hybridization technique requires the formation of DNA duplexes with similar stabilities. In this paper we describe a new strategy to obtain DNA duplexes with a thermal stability independent of their AT/GC ratio content. Melting data were acquired on 35 natural and...

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Udgivet i:Nucleic Acids Res
Principais autores: Nguyen, H K, Bonfils, E, Auffray, P, Costaglioli, P, Schmitt, P, Asseline, U, Durand, M, Maurizot, J C, Dupret, D, Thuong, N T
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147843/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9722646/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.18.4249
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