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T-cell tolerance or function is determined by combinatorial costimulatory signals
Activated in immune responses, T lymphocytes differentiate into effector cells with potent immune function. CD28 is the most prominent costimulatory receptor for T-cell activation. However, absence of CD28 costimulation did not completely impair effector function of CD4 or CD8 T cells. Moreover, inc...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478197/ https://ncbi.nlm.nih.gov/pubmed/16724117 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601146 |
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