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Cdk1 regulates centrosome separation by restraining proteolysis of microtubule-associated proteins
In yeast, separation of duplicated spindle pole bodies (SPBs) (centrosomes in higher eukaryotes) is an indispensable step in the assembly of mitotic spindle and is triggered by severing of the bridge that connects the sister SPBs. This process requires Cdk1 (Cdc28) activation by Tyrosine 19 dephosph...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478175/ https://ncbi.nlm.nih.gov/pubmed/16688214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601136 |
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