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Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient mice
Membranoproliferative glomerulonephritis (MPGN) type II (dense deposit disease) is an inflammatory renal disease characterized by electron-dense deposits and complement C3 on the glomerular basement membrane. There is no effective therapy. We investigated the role of C5 activation in a model of MPGN...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1476693/ https://ncbi.nlm.nih.gov/pubmed/16769899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601094103 |
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