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Detection of known mutation by proof-reading PCR.

Proof-reading PCR (PR-PCR) is designed to detect known mutations within genomic DNA. It differs from standard PCR approaches in that one of the two primers has its 3' end aligned with a putative mutation site, and has its 3'-OH replaced by a blocking group. Distinguishing a mutant gene fro...

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Bibliografski detalji
Glavni autori: Bi, W, Stambrook, P J
Format: Artigo
Jezik:Inglês
Izdano: 1998
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC147629/
https://ncbi.nlm.nih.gov/pubmed/9611257
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