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Inhibition of PNA triplex formation by N4-benzoylated cytosine.

The synthesis of N-((N4-(benzoyl)cytosine-1-yl)acetyl)- N -(2-Boc-aminoethyl)glycine (CBz) and the incorporation of this monomer into PNA oligomers are described. A single CBzresidue within a 10mer homopyrimidine PNA is capable of switching the preferred binding mode from a parallel to an antiparall...

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Published in:Nucleic Acids Res
Main Authors: Christensen, L, Hansen, H F, Koch, T, Nielsen, P E
Format: Artigo
Language:Inglês
Published: Oxford University Press 1998
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147602/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9592162/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.11.2735
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