Ultraviolet Light Induces Redox Reaction–mediated Dimerization and Superactivation of Oncogenic Ret Tyrosine Kinases

The c-RET proto-oncogene encodes a receptor-type tyrosine kinase, and its mutations in the germ line are responsible for the inheritance of multiple endocrine neoplasia type 2A (MEN2A) and 2B (MEN2B). Ret kinases are constitutively activated as a result of MEN2A mutations (Ret-MEN2A) or MEN2B mutati...

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Main Authors: Kato, Masashi, Iwashita, Toshihide, Takeda, Kozue, Akhand, Anwarul A., Liu, Wei, Yoshihara, Motoi, Asai, Naoya, Suzuki, Haruhiko, Takahashi, Masahide, Nakashima, Izumi
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2000
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC14759/
https://ncbi.nlm.nih.gov/pubmed/10637293
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