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REThinking the role of the RET oncogene in breast cancer

The REarranged during Transfection (RET) receptor tyrosine kinase plays a crucial role in the development of various anatomical structures during embryogenesis and it is involved in many physiological cellular processes. This protein is also associated with the initiation of various cancer types, su...

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Autori principali: Giuseppe Di Grazia, Chiara Conti, Sabrina Nucera, Gianmarco Motta, Federica Martorana, Stefania Stella, Michele Massimino, Mario Giuliano, Paolo Vigneri
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2024-08-01
Serie:Frontiers in Oncology
Soggetti:
breast cancer
RET oncogene
targeted therapy
clinical trials
TKI - tyrosine kinase inhibitor
Accesso online:https://www.frontiersin.org/articles/10.3389/fonc.2024.1427228/full
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