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DNA condensation for gene therapy as monitored by atomic force microscopy.

The atomic force microscope (AFM) was used to assay the extent of DNA condensation in approximately 100 different complexes of DNA with polylysine (PL) or PL covalently attached to the glycoproteins asialoorosomucoid (AsOR) or orosomucoid (OR). The best condensation of DNA was obtained with 10 kDa P...

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Detalhes bibliográficos
Main Authors: Hansma, H G, Golan, R, Hsieh, W, Lollo, C P, Mullen-Ley, P, Kwoh, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147577/
https://ncbi.nlm.nih.gov/pubmed/9580703
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