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Distribution of gyrase and topoisomerase IV on bacterial nucleoid: implications for nucleoid organization

We explored the existence of nucleoid DNA loops in Escherichia coli by studying the distribution of bacterial type II topoisomerases (Topo IIs). Norfloxacin-induced high molecular weight (HMW) DNA fragmentation of nucleoid, an event reminiscent of the excision of eukaryotic chromosomal DNA loops med...

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Detalhes bibliográficos
Main Authors: Hsu, Ya-Han, Chung, Meng-Wen, Li, Tsai-Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1475751/
https://ncbi.nlm.nih.gov/pubmed/16757578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl392
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