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Cytarabine-induced destabilization of a model Okazaki fragment.

Cytarabine is a potent anticancer drug that interferes with elongation of the lagging strand at the replication fork during DNA synthesis. The effects of cytarabine substitution on the structural and thermodynamic properties of a model Okazaki fragment were investigated using UV hyperchromicity and...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Gmeiner, W H, Skradis, A, Pon, R T, Liu, J
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 1998
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147563/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2359
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