Cytarabine-induced destabilization of a model Okazaki fragment.

Cytarabine is a potent anticancer drug that interferes with elongation of the lagging strand at the replication fork during DNA synthesis. The effects of cytarabine substitution on the structural and thermodynamic properties of a model Okazaki fragment were investigated using UV hyperchromicity and...

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Publicado en:	Nucleic Acids Res
Autores principales:	Gmeiner, W H, Skradis, A, Pon, R T, Liu, J
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Oxford University Press 1998
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147563/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9580686/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.10.2359
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