Gel electrophoretic detection of 7,8-dihydro-8-oxoguanine and 7, 8-dihydro-8-oxoadenine via oxidation by Ir (IV).

Two gel electrophoretic methods are described for detection of 7, 8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine based on their further oxidation with one-electron oxidants including IrCl62-and IrBr62-. The products of nucleobase oxidation lead to enhanced piperidine-sensitive cleavage and to h...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Muller, J G, Duarte, V, Hickerson, R P, Burrows, C J
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147540/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9547288/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.9.2247
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