The -104G nucleotide of the human CYP21 gene is important for CYP21 transcription activity and protein interaction.

CYP21 gene encodes the steroid 21-hydroxylase (P450c21) that is involved in steroidogenesis in the adrenal cortex. Mutations occurring on CYP21 which convert it to the neighboring pseudogene, CYP21P, are found in patients with congenital adrenal hyperplasia (CAH), an autosomal recessive disease. We...

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Veröffentlicht in:	Nucleic Acids Res
Hauptverfasser:	Chin, K K, Chang, S F
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Oxford University Press 1998
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147502/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9518489/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.8.1959
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