Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines.

DNA polymerase beta is required in mammalian cells for the predominant pathway of base excision repair involving single nucleotide gap filling DNA synthesis. Here we examine the relationship between oxidative stress, cellular levels of DNA polymerase beta and base excision repair capacity in vitro ,...

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Autores principales: Chen, K H, Yakes, F M, Srivastava, D K, Singhal, R K, Sobol, R W, Horton, J K, Van Houten, B, Wilson, S H
Formato: Artigo
Lenguaje:Inglês
Publicado: 1998
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC147493/
https://ncbi.nlm.nih.gov/pubmed/9518496
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