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Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20.

The catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs) is a member of a sub-family of phosphatidylinositol (PI) 3-kinases termed PIK-related kinases. A distinguishing feature of this sub-family is the presence of a conserved C-terminal region downstream of a PI 3-kinase domain. Mutants...

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Published in:Nucleic Acids Res
Main Authors: Priestley, A, Beamish, H J, Gell, D, Amatucci, A G, Muhlmann-Diaz, M C, Singleton, B K, Smith, G C, Blunt, T, Schalkwyk, L C, Bedford, J S, Jackson, S P, Jeggo, P A, Taccioli, G E
Format: Artigo
Language:Inglês
Published: Oxford University Press 1998
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147487/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9518490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.8.1965
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