Reduced susceptibility to ischemic brain injury and N-methyl-d-aspartate-mediated neurotoxicity in cyclooxygenase-2-deficient mice

Cyclooxygenase-2 (COX-2), a prostanoid-synthesizing enzyme that contributes to the toxicity associated with inflammation, has recently emerged as a promising therapeutic target for several illnesses, ranging from osteoarthritis to Alzheimer's disease. Although COX-2 has also been linked to ischemic...

Descrición completa

Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Iadecola, Costantino, Niwa, Kiyoshi, Nogawa, Shigeru, Zhao, Xueren, Nagayama, Masao, Araki, Eiichi, Morham, Scott, Ross, M. Elizabeth
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC14748/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11158633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.98.3.1294
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!