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The Function and Regulation of Budding Yeast Swe1 in Response to Interrupted DNA Synthesis
Periodically regulated cyclin-dependent kinase (Cdk) is required for DNA synthesis and mitosis. Hydroxyurea (HU) inhibits DNA synthesis by depleting dNTPs, the basic unit for DNA synthesis. HU treatment triggers the S-phase checkpoint, which arrests cells at S-phase, inhibits late origin firing and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1474790/ https://ncbi.nlm.nih.gov/pubmed/16571676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-11-1093 |
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