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The processivity of DNA synthesis exhibited by drug-resistant variants of human immunodeficiency virus type-1 reverse transcriptase.

The reverse transcriptase (RT) of human immunodeficiency virus (HIV) undergoes rapid mutagenesis due to selective pressure by RT inhibitors which renders the mutated RT variants resistant to these inhibitors. Resistance to nucleoside analogs during drug therapy results from point mutations that lead...

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Библиографические подробности
Опубликовано в::Nucleic Acids Res
Главные авторы: Avidan, O, Hizi, A
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 1998
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512543/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1713
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