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DNA minor groove recognition by a tetrahydropyrimidinium analogue of hoechst 33258: NMR and molecular dynamics studies of the complex with d(GGTAATTACC)2.

Hoechst 43254 (H43254), a 2,3,4,5-tetrahydropyrimidin-1-ium analogue of the bis-benzimidazole minor groove binding agent Hoechst 33258 (H33258), has been studied by NMR and restrained molecular dynamics in its complex with d(GGTAATTACC)2. We investigate the origin of the enhanced complex stability a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Bostock-Smith, C E, Laughton, C A, Searle, M S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147451/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9512536/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.7.1660
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