Mutations and homologous recombination induced in mammalian cells by metabolites of benzo[a]pyrene and 1-nitropyrene.

Metabolites of two structurally related chemical carcinogens, benzo[a]pyrene and 1-nitropyrene, were compared for their ability to cause cytotoxicity and induce mutations in normally repairing or nucleotide excision repair-deficient diploid human fibroblasts; for their ability to induce mutations in...

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Main Authors: Maher, V M, Patton, J D, Yang, J L, Wang, Y Y, Yang, L L, Aust, A E, Bhattacharyya, N, McCormick, J J
Formato: Artigo
Idioma:Inglês
Publicado: 1987
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474479/
https://ncbi.nlm.nih.gov/pubmed/3129287
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