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Exocytic responses of single leukaemic human cytotoxic T lymphocytes stimulated by agents that bypass the T cell receptor

Cytotoxic T lymphocytes kill targets via secretion of lytic agents including perforin and granzymes. Recently, new methods have been developed to monitor cytotoxic T lymphocyte degranulation. These include detecting the appearance of lysosome-associated membrane protein on the cell's surface, a...

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Autors principals: Pores-Fernando, Arun T, Bauer, Roslyn A, Wurth, Georjeana A, Zweifach, Adam
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474224/
https://ncbi.nlm.nih.gov/pubmed/16020463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.089565
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