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GPR56, an atypical G protein-coupled receptor, binds tissue transglutaminase, TG2, and inhibits melanoma tumor growth and metastasis

The survival and growth of tumor cells in a foreign environment is considered a rate-limiting step during metastasis. To identify genes that may be essential for this process, we isolated highly metastatic variants from a poorly metastatic human melanoma cell line and performed expression analyses o...

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Detalhes bibliográficos
Main Authors: Xu, Lei, Begum, Shahinoor, Hearn, Jeremy D., Hynes, Richard O.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474142/
https://ncbi.nlm.nih.gov/pubmed/16757564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602681103
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