Genetic Variation in the CCL18-CCL3-CCL4 Chemokine Gene Cluster Influences HIV Type 1 Transmission and AIDS Disease Progression

CCL3 (MIP-1α), CCL4 (MIP-1β), and CCL18 (DC-CK1/PARC/AMAC-1) are potent chemoattractants produced by macrophages, natural killer cells, fibroblasts, mast cells, CD4(+) T cells, and CD8(+) T cells. CCL3 and CCL4 are natural ligands for the primary human immunodeficiency virus type 1 (HIV-1) corecepto...

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Main Authors: Modi, William S., Lautenberger, James, An, Ping, Scott, Kevin, Goedert, James J., Kirk, Gregory D., Buchbinder, Susan, Phair, John, Donfield, Sharyne, O’Brien, Stephen J., Winkler, Cheryl
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Human Genetics 2006
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474130/
https://ncbi.nlm.nih.gov/pubmed/16773571
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