Haplotype Homozygosity and Derived Alleles in the Human Genome

Haplotype-based techniques are being used to estimate the relative age of alleles—particularly in screening loci for signals of recent positive selection—but does this approach capture even coarse age differences? Using simulations and empirical data from the International HapMap Project, we show th...

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Main Authors: Fry, Andrew E., Trafford, Clare J., Kimber, Martin A., Chan, Man-Suen, Rockett, Kirk A., Kwiatkowski, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Human Genetics 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474085/
https://ncbi.nlm.nih.gov/pubmed/16685655
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