Serotonin Transporter Promoter Gain-of-Function Genotypes Are Linked to Obsessive-Compulsive Disorder

A functional serotonin transporter promoter polymorphism, HTTLPR, alters the risk of disease as well as brain morphometry and function. Here, we show that HTTLPR is functionally triallelic. The L(G) allele, which is the L allele with a common G substitution, creates a functional AP2 transcription-fa...

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Hlavní autoři: Hu, Xian-Zhang, Lipsky, Robert H., Zhu, Guanshan, Akhtar, Longina A., Taubman, Julie, Greenberg, Benjamin D., Xu, Ke, Arnold, Paul D., Richter, Margaret A., Kennedy, James L., Murphy, Dennis L., Goldman, David
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Human Genetics 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474042/
https://ncbi.nlm.nih.gov/pubmed/16642437
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